Jobs in Sioux Falls, SD, SD

This full-time Registered Nurse role is based at Avera McKennan Hospital within the Postpartum and Gynecology department. The position involves delivering comprehensive nursing care to patients and families, including developing individualized care plans, administering treatments, and providing education on self-management and medications. Key responsibilities also encompass coordinating with multidisciplinary teams, monitoring patient conditions, and maintaining a safe clinical environment through strict adherence to safety protocols. The role offers a rotating shift schedule covering days, nights, weekends, and holidays. It is appealing for its compassionate, multidisciplinary team culture and strong commitment to professional growth through mentorship and hands-on training. Eligible candidates receive paid time off from their first day and access to retirement matching contributions.

This full-time Registered Nurse Case Manager role at Avera McKennan Hospital supports the transition of patients from acute care settings to appropriate levels of post-hospitalization care. The position involves coordinating discharges to skilled nursing facilities, home health services, and rehabilitation centers while collaborating with physicians and payors to ensure efficient, evidence-based treatment. Key responsibilities include managing complex documentation, arranging transportation and medical equipment, and participating in multidisciplinary rounds to maintain continuity of care. The role appeals to nurses seeking a compassionate, mission-driven environment with a strong emphasis on teamwork and patient advocacy. Opportunities for career development through mentorship and hands-on training are available, and the position operates on a day shift schedule within the hospital.

This full-time Registered Nurse role is based at the Avera Medical Group Gastroenterology clinic in Sioux Falls, supporting a multidisciplinary team dedicated to compassionate patient care. The position involves administering medications, assisting providers during procedures, and conducting patient assessments including vital signs and health history. Key responsibilities also include coordinating clinic flow, educating patients on treatments and wellness, and maintaining exam room supplies and lab protocols. The role appeals to professionals seeking a supportive environment that prioritizes compassion and community health, offering immediate paid time off, retirement matching, and mentorship opportunities for career growth. The position operates on a day shift schedule within the clinic setting.

This full-time Registered Nurse role serves as an Oncology Outpatient Clinical Nurse Educator at Avera Cancer Institute in Sioux Falls. The position focuses on staff development, acting as a consultant and change agent to foster clinical excellence through evidence-based practice. Key responsibilities include designing and implementing competency assessments, developing continuing education programs, and collaborating with leadership to establish clinical protocols and care standards. The role appeals to nurses seeking a mission-driven environment that values compassion and professional growth. The organization supports career advancement through mentorship and hands-on training while offering immediate paid time off and retirement matching. The position is based on-site at the Sioux Falls facility.

This full-time Registered Nurse role is based on the Oncology Unit at Avera McKennan Hospital, where the nurse joins a multidisciplinary team dedicated to compassionate patient care. Key responsibilities include developing individualized nursing care plans, administering treatments, and providing physical and emotional support to patients and their families. The position also involves educating patients on self-care and medications while maintaining a safe clinical environment through strict adherence to safety protocols. The role offers a rotating shift schedule including days, evenings, nights, and weekends. It is appealing for its strong emphasis on a supportive culture that values compassion and stewardship, along with opportunities for career development through mentorship and hands-on training.

This full-time nursing role operates as a float position within the Avera Obstetrics & Gynecology Clinic, supporting both Registered Nurses and Licensed Practical Nurses. The team provides professional patient care under provider direction, including administering medications, assisting with examinations and procedures, and managing patient flow and appointment scheduling. Key duties involve screening patients, collecting health histories, documenting medical records, and educating families on wellness and diagnostic processes. The position appeals to candidates seeking a compassionate, multidisciplinary environment focused on moving health forward. Benefits include immediate paid time off, retirement matching, and mentorship opportunities for career development. The role is based on-site at the Plaza 1 location with day shift hours.

This role involves providing specialized nursing care within the Behavioral Health Child Unit at Avera Behavioral Health Center in Sioux Falls. The position serves children and adolescents aged 5 to 17, addressing conditions such as depression, anxiety, and addiction through a structured therapeutic environment. Key responsibilities include developing comprehensive nursing care plans, administering medications, educating patients and families on self-care, and collaborating with a multidisciplinary team to ensure patient safety and recovery. The position offers a flexible self-scheduling program, opportunities for professional growth through mentorship, and a supportive culture focused on compassion and community impact. The role requires a rotating shift schedule including weekends and holidays.

This full-time Registered Nurse role serves as a float pool member within the Behavioral Health department at Avera Behavioral Health Center in Sioux Falls. The position involves rotating shifts across various inpatient units, urgent care, and addiction treatment facilities. Key responsibilities include developing comprehensive nursing care plans, administering physical and psychological support to patients and families, and collaborating with multidisciplinary teams to ensure high-quality outcomes. The role is appealing due to its 100% self-scheduling flexibility, a manageable patient ratio of 7 to 8, and a supportive culture focused on compassion and professional growth. Additionally, the position offers student loan repayment assistance and immediate paid time off, providing significant financial and work-life balance benefits.

This full-time nursing role at Avera Pulmonary & Sleep Medicine in Sioux Falls involves providing professional care to patients within a multidisciplinary team. Key responsibilities include administering medications, performing patient assessments and vitals, assisting providers during procedures, and educating patients on health management and diagnostic processes. The position offers a Monday through Friday schedule with a focus on compassionate care and patient flow. The role is appealing for its supportive culture that prioritizes compassion and professional growth, along with access to student loan repayment assistance and immediate paid time off.

This full-time Registered Nurse role is based at the Avera Pediatric Specialists clinic in Sioux Falls, focusing on pediatric gastrointestinal care within a multidisciplinary team. The position involves administering medications, assisting providers during procedures, and conducting patient assessments including vital signs and health history. Key responsibilities also include coordinating appointment schedules, educating families on treatment plans, and maintaining exam room supplies and lab protocols. The role appeals to candidates seeking a compassionate work environment aligned with the organization's mission to move health forward. It offers immediate paid time off, retirement matching, and structured career development through mentorship and hands-on training.

This full-time nursing role at Avera Medical Group McGreevy-7th Avenue supports patient care within a multidisciplinary clinic team. The position involves administering medications, performing patient assessments, and assisting providers during examinations and procedures. Key responsibilities include coordinating clinic workflows, educating patients on health maintenance, and maintaining accurate medical records. The role appeals to candidates seeking a compassionate work environment focused on moving health forward, offering immediate paid time off, retirement matching, and mentorship for career development. The position operates on a day shift schedule at the specified clinic location.

This full-time nursing role operates within the Avera Behavioral Health Adult Unit in Sioux Falls, providing therapeutic care for adults managing anxiety, depression, and crisis situations. The position involves developing comprehensive nursing care plans, administering medications, and offering physical and emotional support to patients and their families. Key responsibilities include coordinating with a multidisciplinary team, educating patients on self-care strategies, and maintaining a safe, secure environment. The role is appealing due to its flexible scheduling program, a manageable nurse-to-patient ratio, and a supportive culture focused on compassion and professional growth. Opportunities for career development through mentorship and student loan repayment assistance are available. The position requires a rotating shift schedule including days, evenings, nights, weekends, and holidays.

This full-time Registered Nurse role operates within the Behavioral Health Urgent Care team at Avera's Sioux Falls center. The position involves delivering comprehensive nursing care by developing individualized care plans, administering treatments, and providing physical and emotional support to patients and their families. Key responsibilities include collaborating with physicians to coordinate care, educating patients on self-management and medications, and maintaining a safe clinical environment through strict adherence to safety protocols. The role offers a rotating shift schedule covering days, evenings, nights, weekends, and holidays. It is appealing for its compassionate, multidisciplinary culture focused on moving health forward, along with immediate paid time off, retirement matching, and robust career development opportunities including mentorship.

This regular full-time role is based at the Avera Surgical Center in Sioux Falls, where the team supports outpatient robotic and standard surgical procedures. The position involves preparing operating rooms with necessary instruments, assisting surgeons as a scrub person while maintaining sterile fields, and managing equipment sterilization and tracking. The role also includes verifying surgical implants and supporting the training of new staff and students. The position offers a Monday through Friday day shift schedule with a focus on compassionate, multidisciplinary care. It is particularly appealing for new graduates and those seeking career growth through hands-on mentorship, with benefits including immediate paid time off and retirement matching.

This full-time Registered Nurse role supports the long-term care facility at GSS SD Sf Vlg in Sioux Falls, South Dakota, within a not-for-profit Christian organization. The position focuses on providing individualized nursing care to seniors through assessment, care planning, and coordination of treatment across general care, rehab, and memory care units. Key responsibilities include utilizing the nursing process to manage resident health, serving as a charge nurse to delegate tasks, and collaborating with interdisciplinary teams to ensure quality outcomes. The role appeals to professionals seeking a family-oriented environment with opportunities for advancement, education assistance, and a comprehensive benefits package including retirement matching and paid time off. The position operates on a 40-hour evening shift schedule with required weekend and holiday rotations.

This full-time Registered Nurse role serves as a Clinical Care Leader within a large long-term care facility in Sioux Falls, South Dakota, supporting seniors in a Christian not-for-profit environment. The position involves utilizing the nursing process to deliver individualized care, coordinating with inter-professional teams, and supervising unlicensed personnel while ensuring regulatory compliance. Key responsibilities include conducting resident assessments, managing care plans, and providing clinical leadership on departmental committees. The role appeals to experienced nurses seeking a family-oriented culture with significant growth opportunities, including education assistance and advancement pathways. The position offers a comprehensive benefits package, shift differentials, and a collaborative work environment focused on compassionate care.

This full-time CT Technologist role is based at Avera McKennan Hospital and operates on a weekend night shift. The position involves performing CT examinations, preparing patients, adjusting equipment, and producing high-quality diagnostic images for radiologist interpretation. Key responsibilities include screening patients for allergies, maintaining equipment calibration, managing inventory, and mentoring radiology students and staff. The role appeals to candidates seeking a compassionate, multidisciplinary healthcare environment focused on patient care and professional growth. Opportunities include hands-on training, mentorship, and a supportive culture that values compassion and teamwork. The position requires an associate degree in radiologic technology and ARRT certification.

This full-time CT Technologist role at Avera McKennan Hospital supports a multidisciplinary radiology team dedicated to compassionate patient care. The position involves operating specialized CT equipment to produce high-quality diagnostic scans, coordinating examinations for continuity of care, and mentoring students and staff members to enhance departmental proficiency. Key responsibilities also include maintaining equipment quality, reporting malfunctions, and adhering to strict safety and regulatory standards. The role offers a supportive environment focused on professional growth through hands-on training and mentorship, with benefits including immediate paid time off and retirement matching. The position operates primarily on nights with rotating weekends and holidays.

This role is for experienced CDL-A owner operators seeking to run their own trucking business with F2F Transport. The position offers flexibility to choose between the Connect Program for independent load booking or the Direct Program for dedicated routes with 24/7 operational support. Key responsibilities include managing dry van, power-only, flatbed, or reefer equipment on OTR, regional, or local routes while maintaining compliance with safety regulations. The opportunity is appealing due to the 80% gross pay structure, weekly settlements, and comprehensive support including covered DOT inspections, maintenance escrow, and cargo insurance. Drivers benefit from a collaborative culture with dedicated load planners and virtual orientation, operating with freedom and independence across various route types.

This travel nursing role places a Registered Nurse in the Emergency Room and Trauma unit of a tertiary care facility in Sioux Falls, South Dakota. The position involves managing high-acuity patients in a 16-bed private room setting with 30,000 annual visits. Key responsibilities include delivering acute care, utilizing EPIC electronic health records, and maintaining certifications such as BLS, ACLS, PALS, and TNCC. The six-week contract offers a 36-hour work week with free private housing and comprehensive benefits including medical, dental, and vision coverage. The role appeals to professionals seeking to work in a revitalized city known for its arts and culture while advancing their skills in a fast-paced trauma environment.

This travel nursing role places a Registered Nurse in the Emergency Room and Trauma unit of a tertiary care facility in Sioux Falls, South Dakota. The position involves managing high-acuity patients in a 16-bed private room unit handling 30,000 annual visits. Key responsibilities include providing acute care, utilizing EPIC electronic health records, and maintaining certifications such as ACLS, PALS, and TNCC. The assignment offers a six-week contract with a 36-hour weekly schedule. The role is appealing for its opportunity to work in a revitalized city known for its arts and culture, while the agency provides free private housing, comprehensive health benefits, and continuing education. This position supports professional growth by fostering adaptability and resilience through exposure to diverse patient populations and dynamic clinical environments.

This full-time travel nursing role places a Registered Nurse in the Medical-Surgical unit at a facility in Sioux Falls, South Dakota. The position covers an eight-week night shift contract starting in May 2026. Key responsibilities include delivering patient care, maintaining professional standards during high-stress situations, and collaborating with the healthcare team. The role is appealing due to the comprehensive benefits package, which includes health insurance, housing options, and a 401(k) match, alongside 24/7 support and a traveler-first culture. Candidates must hold a valid nursing license and driver's license to participate in this flexible arrangement.