Nucleic-Acid Biochemistry Jobs

This contractor role supports the Genomics Assay Development team at Freenome, focusing on creating life-saving early cancer detection diagnostics. The position involves developing, characterizing, and validating clinical-grade assays using next-generation sequencing and robotic platforms. Key responsibilities include designing and executing complex molecular biology experiments, analyzing data, and collaborating with engineering and clinical teams to transition protocols into production within a regulated environment. The opportunity appeals to candidates passionate about genomics and diagnostics, offering a chance to significantly impact a mission-driven organization. The role is based onsite at the company's headquarters in Brisbane, California.

This senior leadership role directs formulation and process development for a diverse portfolio of patient-centered injectable drug products at Alexion. The position involves leading end-to-end development from pre-clinical stages through licensure, managing technology transfers, and defining strategic roadmaps for peptide, protein, and gene delivery modalities. Key responsibilities include mentoring scientific teams, overseeing budget management, and collaborating with cross-functional partners in operations, quality, and regulatory affairs to ensure successful product registration. The role is appealing for its opportunity to drive innovation in complex drug delivery formats within a mission-driven environment focused on rare diseases. This is an on-site position based in the Product Development and Clinical Supplies department.

The Scientist, RNA Chemistry role is based on-site in Waltham, MA, within the Platform team at Dyne Therapeutics, a company dedicated to developing therapeutics for genetically driven neuromuscular diseases. The position focuses on the independent design and execution of oligonucleotide synthesis, purification, and analysis to support the discovery of novel nucleic acid treatments. Key responsibilities include synthesizing modified RNA oligonucleotides for in vitro and in vivo studies, troubleshooting and optimizing production methods, and interpreting analytical data to ensure high purity and yield. The role appeals to candidates seeking to contribute to a mission-driven environment addressing serious diseases, offering opportunities for technical growth in state-of-the-art laboratories and cross-functional collaboration.