Postdoctoral Research Associate
Not Disclosed•InternOn-site
location_on750, Weaver Dairy Road, Carol Woods, Chapel Hill, Orange County, North Carolina, 27514, United States
About the Team
The Heinzen laboratory, within the Division of Pharmacotherapy and Experimental Therapeutics at the University of North Carolina at Chapel Hill's Eshelman School of Pharmacy, operates in a highly interdisciplinary environment. In collaboration with the Eshelman Institute for Innovation, the team focuses on identifying convergent disease mechanisms and drug targets across multiple types of genetic epilepsies.
About the Role
We are seeking postdoctoral fellows to study the molecular mechanisms of genetic epilepsies. Successful candidates will develop induced pluripotent stem cell-derived neuronal models and apply cutting-edge technologies, including electrophysiology, single-cell RNAseq, chromatin conformation capture, optogenetics, genetic-encoded biosensors, and live cell imaging. The work involves analyzing cellular and molecular signatures associated with these conditions, which will then feed into the drug discovery pipeline or undergo CRISPR screens to identify druggable genetic modifiers.
The ultimate goal of this fellowship is to help you develop specialized skill sets that drive independent research programs and launch independent research careers. The position involves a significant amount of laboratory bench work and requires excellent communication, organization, and writing skills, as well as a willingness to engage in collaborative team science.
Work location
Work model: On-site
750, Weaver Dairy Road, Carol Woods, Chapel Hill, Orange County, North Carolina, 27514, United States
Chapel Hill, North Carolina
Key Responsibilities
- check_circleDevelop induced pluripotent stem cell derived neuronal models of genetic epilepsies
- check_circleApply electrophysiology and single-cell RNAseq to study cellular signatures
- check_circleDrive independent research programs to launch independent research careers
- check_circleConduct CRISPR screens to identify druggable genetic modifiers
- check_circleFeed cellular and molecular signatures into the drug discovery pipeline
- check_circleUtilize chromatin conformation capture and optogenetics for molecular analysis
Nice to Have
Research experience with human induced pluripotent stem cell models
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Frequently asked questions about Postdoctoral Research Associate at UNC Health
What does a Postdoctoral Research Associate at UNC Health do?expand_more
In this Postdoctoral Research Associate at UNC Health role, you will develop induced pluripotent stem cell derived neuronal models of genetic epilepsies; apply electrophysiology and single-cell rnaseq to study cellular signatures; drive independent research programs to launch independent research careers; and conduct crispr screens to identify druggable genetic modifiers.
Where is the Postdoctoral Research Associate role at UNC Health located?expand_more
Postdoctoral Research Associate at UNC Health is based in 750, Weaver Dairy Road, Carol Woods, Chapel Hill, Orange County, North Carolina, 27514, United States. This is a on-site role.
Is this Postdoctoral Research Associate job remote, hybrid, or on-site?expand_more
UNC Health has listed this Postdoctoral Research Associate role as on-site.
How much experience is required for this Postdoctoral Research Associate role?expand_more
Candidates for Postdoctoral Research Associate at UNC Health should have mid level.
What skills do you need for the Postdoctoral Research Associate role at UNC Health?expand_more
Key skills for Postdoctoral Research Associate at UNC Health include Electrophysiology; Single-Cell Rnaseq; Chromatin Conformation Capture Technique; Optogenetics; Genetic Encoded Biosensors Of Neurotransmission; Live Cell Imaging; Crispr-Screens; and Induced Pluripotent Stem Cell.
What category does the Postdoctoral Research Associate role belong to?expand_more
Postdoctoral Research Associate at UNC Health is part of the scientific & qa job category on Recrutus.