Jobs
Locationsexpand_more
All locations
Jobs in TexasJobs in CaliforniaJobs in New YorkJobs in FloridaJobs in North CarolinaJobs in Virginia
Categoriesexpand_more
All categories
Healthcare & NursingLogistics & WarehouseEngineeringITSalesHospitality & Catering
SkillsCompaniesCareer GuidesBlogSalary
JobsLocationsCategoriesCompaniesCareer GuidesBlogSalary

Top states

TexasCaliforniaNew YorkFloridaNorth CarolinaVirginia

Top categories

Healthcare & NursingLogistics & WarehouseEngineeringITSalesHospitality & Catering
Recrutus

Curating the world's most innovative career opportunities. We bridge the gap between visionary talent and industry-leading companies.

Search roles by city, category, skill, or job type — explore verified US employers, salary benchmarks, and remote-friendly teams hiring nationwide.

publiclanguageshare
Job seekers
Browse jobsCompanies hiringRemote jobsJobs by locationJobs by cityJobs by categoryJobs by skillCareer guidesCareer blogSalary insights
Job types
Contractor jobsFull-Time jobsIntern jobsOther jobsPart-Time jobsPer-Diem jobsTemporary jobsVolunteer jobs
Top states
Jobs in TexasJobs in CaliforniaJobs in New YorkJobs in FloridaJobs in North CarolinaJobs in VirginiaAll states →
Top categories
Healthcare & Nursing jobsLogistics & Warehouse jobsEngineering jobsIT jobsSales jobsHospitality & Catering jobsAccounting & Finance jobs
Popular skills
CDL A jobsExcel jobsEnglish jobsMicrosoft Office jobs
Featured employers
Company
About usFAQContactPrivacy policyUS privacy noticeAccessibility

Recrutus helps candidates discover roles that match their skills and helps teams reach qualified applicants faster. Browse by metro, discipline, or work style — from internships to senior leadership.

© 2026 Recrutus. All rights reserved.
Terms of serviceCookie policyAcceptable useDMCA policyEmployer termsCandidate terms
Jobs
Locationsexpand_more
All locations
Jobs in TexasJobs in CaliforniaJobs in New YorkJobs in FloridaJobs in North CarolinaJobs in Virginia
Categoriesexpand_more
All categories
Healthcare & NursingLogistics & WarehouseEngineeringITSalesHospitality & Catering
SkillsCompaniesCareer GuidesBlogSalary
JobsLocationsCategoriesCompaniesCareer GuidesBlogSalary

Top states

TexasCaliforniaNew YorkFloridaNorth CarolinaVirginia

Top categories

Healthcare & NursingLogistics & WarehouseEngineeringITSalesHospitality & Catering
Recrutus

Curating the world's most innovative career opportunities. We bridge the gap between visionary talent and industry-leading companies.

Search roles by city, category, skill, or job type — explore verified US employers, salary benchmarks, and remote-friendly teams hiring nationwide.

publiclanguageshare
Job seekers
Browse jobsCompanies hiringRemote jobsJobs by locationJobs by cityJobs by categoryJobs by skillCareer guidesCareer blogSalary insights
Job types
Contractor jobsFull-Time jobsIntern jobsOther jobsPart-Time jobsPer-Diem jobsTemporary jobsVolunteer jobs
Top states
Jobs in TexasJobs in CaliforniaJobs in New YorkJobs in FloridaJobs in North CarolinaJobs in VirginiaAll states →
Top categories
Healthcare & Nursing jobsLogistics & Warehouse jobsEngineering jobsIT jobsSales jobsHospitality & Catering jobsAccounting & Finance jobs
Popular skills
CDL A jobsExcel jobsEnglish jobsMicrosoft Office jobs
Featured employers
Company
About usFAQContactPrivacy policyUS privacy noticeAccessibility

Recrutus helps candidates discover roles that match their skills and helps teams reach qualified applicants faster. Browse by metro, discipline, or work style — from internships to senior leadership.

© 2026 Recrutus. All rights reserved.
Terms of serviceCookie policyAcceptable useDMCA policyEmployer termsCandidate terms
Jobs
Locationsexpand_more
All locations
Jobs in TexasJobs in CaliforniaJobs in New YorkJobs in FloridaJobs in North CarolinaJobs in Virginia
Categoriesexpand_more
All categories
Healthcare & NursingLogistics & WarehouseEngineeringITSalesHospitality & Catering
SkillsCompaniesCareer GuidesBlogSalary
JobsLocationsCategoriesCompaniesCareer GuidesBlogSalary

Top states

TexasCaliforniaNew YorkFloridaNorth CarolinaVirginia

Top categories

Healthcare & NursingLogistics & WarehouseEngineeringITSalesHospitality & Catering
  1. Home
  2. chevron_right
  3. it
  4. chevron_right
  5. Principal Software Engineer
Amgen logo

Principal Software Engineer

Not Disclosed•Full-TimeOn-site

location_on791, West River Heights Avenue, River Haven, Tampa, Hillsborough County, Florida, 33603, United States

Apply Now

Join Amgen's Mission of Serving Patients

At Amgen, you are part of something bigger. Our shared mission to serve patients living with serious illnesses drives everything we do. Since 1980, we have helped pioneer the world of biotech in our fight against the world's toughest diseases. With a focus on four therapeutic areas—Oncology, Inflammation, General Medicine, and Rare Disease—we reach millions of patients each year. We are advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity-related conditions.

As a member of the Amgen team, you will help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller, happier lives. Our award-winning culture is collaborative, innovative, and science-based. If you have a passion for challenges and the opportunities that lie within them, you will thrive as part of the Amgen team. Join us to transform the lives of patients while transforming your career.

About the Role

In this vital role, you will play a pivotal part in shaping our technology strategy and mentoring a team of talented engineers. You will take ownership of complex software projects from conception to deployment, managing scope, risk, and timelines. This position requires a blend of hands-on development and strategic leadership, where you will contribute to both front-end and back-end development using cloud technology. You will be at the forefront of innovation, developing solutions using generative AI technologies and defining robust software architectures on the cloud (AWS preferred). Beyond technical execution, you will lead and motivate your team, conduct code reviews to ensure quality, and create comprehensive documentation on architecture, design, and operations. You will work closely with product, business, and other stakeholders to identify and resolve technical challenges effectively.

What You Can Expect

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we will support your journey every step of the way. We offer flexible work models where possible, allowing you to balance your professional responsibilities with your personal life.

Application Process

Amgen does not have a specific application deadline for this position; we will continue accepting applications until we receive a sufficient number of candidates or select a successful candidate. In any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.

Our Commitment to Diversity and Inclusion

As an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed, and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.

Amgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law. We will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.

Work location

Work model: On-site

location_on

791, West River Heights Avenue, River Haven, Tampa, Hillsborough County, Florida, 33603, United States

Tampa, Florida

Key Responsibilities

  • check_circleTranslate concepts into working code using rapid prototyping skills
  • check_circleTake ownership of complex software projects from conception to deployment
  • check_circleContribute to front-end and back-end development using cloud technology
  • check_circleDefine and implement robust software architectures on AWS
  • check_circleLead and motivate a team of engineers to deliver high-quality results
  • check_circleConduct code reviews to ensure code quality and adherence to best practices
  • check_circleCreate and maintain documentation on software architecture and disaster recovery
  • check_circleIdentify and resolve technical challenges effectively
  • check_circleShape technology strategy and mentor a team of talented engineers
  • check_circleDevelop innovative solutions using generative AI technologies

Requirements

  • verifiedDoctorate degree and 2 years of experience OR Master's degree and 4 years of experience OR Bachelor's degree and 6 years of experience OR Associate's degree and 10 years of experience OR High school diploma / GED and 12 years of experience
  • verifiedHands on experience with various cloud services
  • verifiedHands on experience with Full Stack software development
  • verifiedProficient in programming language Python, JavaScript, SQL/NoSQL
  • verifiedProven ability to lead and mentor software development teams
  • verifiedBachelor's degree in computer science and engineering preferred, other Engineering field is considered; Master's degree and 6+ years of software development experience Or Bachelor's degree and 8+ years of software development experience
  • verifiedCloud Computing certificate preferred

Nice to Have

Experience with API integration, serverless, and microservices architecture. Experience in SQL/NoSQL databases, specifically vector databases for large language models. Experience with popular large language models, Langchain or LlamaIndex frameworks, prompt engineering, and model fine-tuning. Experience with website development and localization processes. Experience with DevOps/MLOps CI/CD build and deployment pipelines. Knowledge of design patterns, data structures, test-driven development, and NLP techniques for text analysis and sentiment analysis. Bachelor's degree in computer science and engineering (or other engineering fields). Master's degree with 6+ years of software development experience, or Bachelor's degree with 8+ years of software development experience. Cloud Computing certificate.

Benefits & Perks

check_circleRetirement and Savings Plan with generous company contributionscheck_circleGroup medical, dental, and vision coveragecheck_circleLife and disability insurancecheck_circleFlexible spending accountsDiscretionary annual bonus program
Amgen logo
Company

Amgen

Industry

it

View company profilearrow_forwardlanguageWebsite
Quick Overview

Experience

2-12 yrs (Lead)

Education

Doctorate degree required with 2 years of experience

Job Type

Full-Time

Skills Required

Similar Job Opportunities

NetApp logo

Software Engineer

NetApp • San Jose, California

$160k-215karrow_forward
Openkyber logo

Senior API Management Engineer

Openkyber • Remote

Not Disclosedarrow_forward
Eli Lilly and Company logo

Software Engineer, AI & Clinical Applications

Eli Lilly and Company • Indianapolis, Indiana

$65k-158karrow_forward

Skills, education and keywords

Skills: Python, Javascript, SQL, Nosql, Aws, Api Integration, Serverless, Microservices Architecture, Vector Database, Langchain.

Education: Doctorate degree required with 2 years of experience; Master's degree required with 4 years of experience; Bachelor's in Computer Science and Engineering preferred.

Frequently asked questions about Principal Software Engineer at Amgen

What does a Principal Software Engineer at Amgen do?expand_more
Day-to-day, the Principal Software Engineer at Amgen will translate concepts into working code using rapid prototyping skills; take ownership of complex software projects from conception to deployment; contribute to front-end and back-end development using cloud technology; and define and implement robust software architectures on aws.
What are the requirements for this Principal Software Engineer role?expand_more
Amgen is looking for candidates who meet the following requirements: Doctorate degree and 2 years of experience OR Master's degree and 4 years of experience OR Bachelor's degree and 6 years of experience OR Associate's degree and 10 years of experience OR High school diploma / GED and 12 years of experience; Hands on experience with various cloud services; Hands on experience with Full Stack software development; Proficient in programming language Python, JavaScript, SQL/NoSQL; Proven ability to lead and mentor software development teams; and Bachelor's degree in computer science and engineering preferred, other Engineering field is considered; Master's degree and 6+ years of software development experience Or Bachelor's degree and 8+ years of software development experience.
Where is the Principal Software Engineer role at Amgen located?expand_more
Principal Software Engineer at Amgen is based in 791, West River Heights Avenue, River Haven, Tampa, Hillsborough County, Florida, 33603, United States. This is a on-site role.
Is this Principal Software Engineer job remote, hybrid, or on-site?expand_more
Amgen has listed this Principal Software Engineer role as on-site.
How much experience is required for this Principal Software Engineer role?expand_more
Principal Software Engineer at Amgen typically requires 2–12 years of relevant experience at the lead level.
What skills do you need for the Principal Software Engineer role at Amgen?expand_more
Key skills for Principal Software Engineer at Amgen include Python; Javascript; SQL; Nosql; Aws; Api Integration; Serverless; and Microservices Architecture.
What education is required for Principal Software Engineer at Amgen?expand_more
Educational requirements for this role: Doctorate degree required with 2 years of experience; Master's degree required with 4 years of experience; and Bachelor's in Computer Science and Engineering preferred.
What category does the Principal Software Engineer role belong to?expand_more
Principal Software Engineer at Amgen is part of the it job category on Recrutus.
Recrutus

Curating the world's most innovative career opportunities. We bridge the gap between visionary talent and industry-leading companies.

Search roles by city, category, skill, or job type — explore verified US employers, salary benchmarks, and remote-friendly teams hiring nationwide.

publiclanguageshare
Job seekers
Browse jobsCompanies hiringRemote jobsJobs by locationJobs by cityJobs by categoryJobs by skillCareer guidesCareer blogSalary insights
Job types
Contractor jobsFull-Time jobsIntern jobsOther jobsPart-Time jobsPer-Diem jobsTemporary jobsVolunteer jobs
Top states
Jobs in TexasJobs in CaliforniaJobs in New YorkJobs in FloridaJobs in North CarolinaJobs in VirginiaAll states →
Top categories
Healthcare & Nursing jobsLogistics & Warehouse jobsEngineering jobsIT jobsSales jobsHospitality & Catering jobsAccounting & Finance jobs
Popular skills
CDL A jobsExcel jobsEnglish jobsMicrosoft Office jobs
Featured employers
Company
About usFAQContactPrivacy policy

Recrutus helps candidates discover roles that match their skills and helps teams reach qualified applicants faster. Browse by metro, discipline, or work style — from internships to senior leadership.

© 2026 Recrutus. All rights reserved.
Terms of serviceCookie policyAcceptable useDMCA policyEmployer termsCandidate terms
  • check_circleCollaborate with product, business teams, and other stakeholders
  • check_circle
    check_circleStock-based long-term incentives
    check_circleAward-winning time-off plans
    check_circleFlexible work models where possible
    Python
    Javascript
    SQL
    Nosql
    Aws
    Api Integration
    Serverless
    Microservices Architecture
    Vector Database
    Langchain
    US privacy notice
    Accessibility