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  1. Home
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  5. Associate Director, in vitro Pharmacology
Deep Genomics logo

Associate Director, in vitro Pharmacology

Not Disclosed•Full-TimeOn-site

location_on127, Lakeview Avenue, Huron Village, West Cambridge, Cambridge, Middlesex County, Massachusetts, 02140, United States

Apply Now

About Us

Deep Genomics is at the forefront of using artificial intelligence to transform drug discovery. Our proprietary AI platform decodes the complexity of RNA biology to identify novel drug targets, mechanisms, and therapeutics inaccessible through traditional methods. With expertise spanning machine learning, bioinformatics, data science, engineering, and drug development, our multidisciplinary team in Toronto and Cambridge, MA is revolutionizing how new medicines are created.

About the Role

The Associate Director, in vitro pharmacology will lead the target validation function at Deep Genomics with the goal of advancing our RNA editing therapeutics portfolio. This is a leadership role designed to make a significant impact on the therapeutic pipeline, requiring the ability to lead strategically, execute tactically, and influence others in a highly matrixed and multidisciplinary team.

As a key member of an early-stage discovery team, you will demonstrate initiative and ownership in both scientific and strategic decisions with an entrepreneurial mindset. You will work closely with therapeutic program teams and the Target Identification team to translate AI-derived target nominations into clear action plans leading to go/no-go decisions. Success in this role involves leading from the bench while supervising junior scientists directly and indirectly, anticipating needs proactively, and independently seeking solutions.

Hiring Process

Deep Genomics encourages applications from all backgrounds who seek the opportunity to build the world's leading AI-driven genetic medicine company. If you have a disability or special need, accommodation is available on request for candidates taking part in all aspects of the selection process.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment; final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.

Work location

Work model: On-site

location_on

127, Lakeview Avenue, Huron Village, West Cambridge, Cambridge, Middlesex County, Massachusetts, 02140, United States

Cambridge, Massachusetts

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Key Responsibilities

  • check_circleLead all aspects of liver biology target validation from strategy to execution and interpretation
  • check_circleServe as senior subject matter expert for in vitro pharmacology strategy and liver biology
  • check_circleCollaborate with Target Identification team to assess feasibility of in vitro models for new targets
  • check_circlePresent clear, data-driven go/no-go decisions on novel therapeutic targets
  • check_circleAnalyze, interpret, and present complex data to scientists and management in internal and external venues
  • check_circleMentor direct and indirect reports while demonstrating strong leadership and accountability

Requirements

  • verifiedPhD in biological sciences
  • verified6+ years post-graduate experience in in vitro pharmacology
  • verified3+ years building, managing, and leading teams
  • verifiedHands-on experience with in vitro liver disease models
  • verifiedHands-on experience with functional assays (steatosis, inflammation, fibrosis)
  • verifiedHands-on experience with gene editing or oligonucleotide therapeutics

Nice to Have

Experience with advanced in vitro liver models (e.g., iPSC derived cells, organoids, co-culture systems). Prior experience executing studies with contract research organizations. Experience planning and writing regulatory packages including IND submissions. Understanding of target discovery via human genetics. Strong computational background or demonstrated ability to interface with computational biology teams.

Benefits & Perks

check_circleComprehensive health, vision, and dental coverage for employees and familiescheck_circleEmployee and family assistance programcheck_circleFlexible work environment with flexible hours and extended long weekendscheck_circleUnlimited personal days and holiday shutdowncheck_circleMaternity and parental leave top-up coveragecheck_circleNew parent paid time offcheck_circleLearning and development budgetcheck_circleLunch and learns sessions
Deep Genomics cover image
Deep Genomics logo
Company

Deep Genomics

Industry

Biotechnology Research

Headquarters

Toronto

Open Roles

1

Deep Genomics is a biotechnology research company headquartered in Toronto that leverages artificial intelligence to address complex molecular design and target biology challenges. The organization operates by integrating multiple disciplines to overcome historical limitations in drug discovery that traditionally relied on slow, empirical methods. At the core of its operations is the Biological Foundation Model Platform, a unified engine designed to streamline the development of new medicines. This platform combines lab-in-the-loop workflows, AI model refinement, specialized training datasets, and advanced screening technologies within a single architecture. By utilizing this common foundation, the firm builds and improves biological models to identify molecules and targets that other approaches might overlook. The ultimate objective is to accelerate the development of these findings into effective treatments for patients, transforming the broader landscape of pharmaceutical research through data-driven innovation and computational biology.
View company profilearrow_forwardlanguageWebsitelinkLinkedIn
Quick Overview

Experience

6+ yrs (Lead)

Education

PhD in biological sciences with 6+ years of post-graduate experience (or equivalent)

Job Type

Full-Time

Skills Required

Artificial IntelligenceMachine LearningBioinformaticsData ScienceDrug DiscoveryIn Vitro Pharmacology
Not Disclosedarrow_forward
Recrutus

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Target Validation
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