The Head of Computational Chemistry leads the computational, cheminformatics, and molecular design functions at General Proximity, a seed-stage biotech pioneering induced proximity medicines. This role combines strategic leadership with hands-on drug design, guiding small-molecule programs from hit identification through candidate selection using advanced modeling techniques like docking, molecular dynamics, and free-energy methods. Key responsibilities include building scalable cheminformatics infrastructure, integrating AI and machine learning tools to accelerate design-make-test-analyze cycles, and collaborating closely with medicinal chemists and structural biologists to optimize compound properties. The position offers the opportunity to establish a modern, AI-enabled platform from the ground up within a high-energy, writing-first culture that values scientific ownership and rapid growth. The role is based on-site at the MBC BioLabs in the Bay Area with flexible working hours.