Research Assistant - Neuroscience and Pharmacology (Tomchik Lab) - Stem Cell Research
Not Disclosed•Full-TimeOn-site
location_on10, South Gilbert Street, Iowa City, Johnson County, Iowa, 52240, United States
The Carver College of Medicine Department of Neuroscience and Pharmacology, specifically the Dr. Tomchik lab, is dedicated to understanding the mechanisms of metabolic alterations in genetic disorders. Our research broadly focuses on neuronal plasticity and metabolic changes in Neurofibromatosis type 1 (NF1), a disease affecting approximately 1 in 3,000 individuals that causes tumor formation, neurocognitive symptoms, and metabolic issues.
Building on our recent discovery that the loss of neurofibromin alters metabolic rate via neuronal effects, this project dives deeper into the underlying mechanisms. The College's mission is to inspire and educate world-class healthcare providers and scientists for the people of Iowa and the global community. Researchers in our over 280 laboratories are supported by state-of-the-art core facilities, fostering interdisciplinary collaboration through major research centers and institutes. Our faculty includes internationally renowned scientists, with members of the Howard Hughes Medical Institute, the Institute of Medicine, and the National Academy of Sciences.
This Research Assistant position offers a unique opportunity to conduct research at the intersection of neuroscience and metabolism using both human induced pluripotent stem cells (iPSCs) and Drosophila melanogaster. You will work in a dynamic environment to investigate how genetic mutations impact metabolic function.
In this role, you will carry out cell culture experiments, maintain human iPSC lines, and differentiate them into various cell types for biochemical, physiological, and morphological analysis. You will also manage Drosophila stocks, perform genetic crosses, and conduct metabolic analyses across both model systems. The position requires working independently to set up experiments, troubleshoot protocols, and track progress toward research goals, while also collaborating with other researchers within the lab and across units. You will be expected to read and review research literature to develop hypotheses, present findings at lab meetings and conferences, and assist in preparing manuscripts for publication.
To be considered for this position, applicants must upload a CV or resume and a cover letter that clearly addresses how they meet the listed required and desired qualifications. Job openings are posted for a minimum of 7 calendar days and may be filled at any time after the posting period ends. Successful candidates will be required to self-disclose any conviction history and will be subject to a criminal background check and credential/education verification. Up to five professional references will be requested at a later stage in the recruitment process. Please note that this position is not eligible for employment sponsorship.
For additional questions, please contact Anne Beyerink at anne-phillips@uiowa.edu.
The University of Iowa is an Equal Opportunity/Affirmative Action employer. We are committed to creating a diverse and inclusive environment for all employees and students.
Work model: On-site
10, South Gilbert Street, Iowa City, Johnson County, Iowa, 52240, United States
Iowa City, Iowa
Experience with cell culture / iPSCs, Experience with Drosophila, Basic histology techniques (e.g., immunohistochemistry) and/or biochemistry techniques (e.g., western blots), Experience with microscopy, Familiarity with Prism and/or Illustrator
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Skills: Cell Culture, Ipscs, Drosophila, Immunohistochemistry, Western Blots, Microscopy, Prism, Illustrator, Microsoft Office.
Education: Bachelor's degree in a biomedical related field or equivalent experience.