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  1. Home
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  5. Principal Data Science Engineer - AI/ML & Algorithms
TransMedics, Inc. logo

Principal Data Science Engineer - AI/ML & Algorithms

Not Disclosed•Full-TimeOn-site

location_on11, Summer Street, Andover, Essex County, Massachusetts, 01810, United States

Apply Now

About the Mission

Every Organ Wasted is a Life Not Saved. TransMedics, Inc. is a commercial-stage medical technology company transforming organ transplant therapy for patients worldwide. Our mission is to help save more patients' lives by increasing access to viable donor organs for those who are awaiting an organ transplant. To accomplish this, we partner closely with transplant stakeholders worldwide to expand access to healthy donor organs while delivering the highest quality technology, service, clinical care, and outcomes.

Driven by a passion for improving patient care, we make the impossible possible and keep our employees at the center of everything we do. Together, we strive to enhance the quality of life for transplant recipients and their families, fostering hope and healing in the journey toward better health.

About the Role

We are seeking a talented and driven Principal Data Science Engineer to join our team. In this role, you will have the opportunity to develop intelligent, data-driven solutions to improve patient outcomes and clinical workflows. You will contribute to the lifecycle of embedded and digital clinical software applications that monitor, control, and preserve donated hearts, lungs, livers, and other organs on the Organ Care System (OCS).

You will work collaboratively with clinical leads, software engineers, and product teams to translate clinical needs into technical specifications. Your work will involve designing, training, and validating machine learning and traditional algorithms for clinical decision support and automation, ensuring all data handling adheres to strict regulatory standards including HIPAA and GDPR. You will also guide clinical algorithmic strategy, perform reviews, and set best practices for development and validation, while explaining complex technical concepts to non-technical stakeholders.

Company Growth & Culture

As part of our long-term growth plans, TransMedics is excited to announce our plan to relocate our headquarters to Somerville, MA by 2028. We chose this location because we believe it is a place where innovation will thrive. Our new state-of-the-art headquarters is designed to support collaboration, creativity, and discovery, allowing us to continue doing things few thought possible in organ transplantation to help patients.

TransMedics is committed to equitable and transparent compensation and does not request or consider salary history. We are an equal opportunity employer and do not discriminate on the basis of race, color, religion, sex, national origin, marital status, age, disability, or protected veteran status. We are committed to creating an inclusive environment for all employees.

Important Application Note

Please note that this position is not available for visa sponsorship, and we are unable to take over existing employment visa sponsorships.

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Frequently asked questions about Principal Data Science Engineer - AI/ML & Algorithms at TransMedics, Inc.

What does a Principal Data Science Engineer - AI/ML & Algorithms at TransMedics, Inc. do?expand_more
In this Principal Data Science Engineer - AI/ML & Algorithms at TransMedics, Inc. role, you will design, train, and validate machine learning and traditional algorithms for clinical decision support; manage end-to-end lifecycle of data-driven software products from exploration to deployment; ensure all data handling adheres to strict regulatory standards including hipaa and gdpr; and implement data anonymization, pseudonymization, and secure access controls for patient information.
What are the requirements for this Principal Data Science Engineer - AI/ML & Algorithms role?expand_more
TransMedics, Inc. is looking for candidates who meet the following requirements: BS/MS in Computer Science, Data Science, Engineering, Mathematics, or equivalent; 3+ years building and deploying machine learning solutions; 8+ years overall software development experience; No visa sponsorship available; Proficiency in Python; and Experience with PyTorch.
Where is the Principal Data Science Engineer - AI/ML & Algorithms role at TransMedics, Inc. located?expand_more
Principal Data Science Engineer - AI/ML & Algorithms at TransMedics, Inc. is based in 11, Summer Street, Andover, Essex County, Massachusetts, 01810, United States. This is a on-site role.
Is this Principal Data Science Engineer - AI/ML & Algorithms job remote, hybrid, or on-site?expand_more

Work location

Work model: On-site

location_on

11, Summer Street, Andover, Essex County, Massachusetts, 01810, United States

Andover, Massachusetts

Key Responsibilities

  • check_circleDesign, train, and validate machine learning and traditional algorithms for clinical decision support
  • check_circleManage end-to-end lifecycle of data-driven software products from exploration to deployment
  • check_circleEnsure all data handling adheres to strict regulatory standards including HIPAA and GDPR
  • check_circleImplement data anonymization, pseudonymization, and secure access controls for patient information
  • check_circleGuide clinical algorithmic strategy and set best practices for development and validation
  • check_circleExplain clinical algorithmic strategy and complex technical concepts to non-technical stakeholders
  • check_circleCollaborate with clinical leads and engineers to translate clinical needs into technical specifications

Requirements

  • verifiedBS/MS in Computer Science, Data Science, Engineering, Mathematics, or equivalent
  • verified3+ years building and deploying machine learning solutions
  • verified8+ years overall software development experience
  • verifiedNo visa sponsorship available
  • verifiedProficiency in Python
  • verifiedExperience with PyTorch
  • verifiedKnowledge of SQL and NoSQL databases
  • verifiedExperience with AWS data engineering services

Nice to Have

Experience in the healthcare or life sciences industry. Understanding of data privacy regulations like HIPAA and GDPR. Knowledge of medical device software development with compliance to IEC-62304 and FDA guidelines. Experience in C/C++ programming language.

Benefits & Perks

check_circleMedical, dental, and vision insurancecheck_circleHealth Reimbursement Account through Blue Cross/Blue Shieldcheck_circleHealthcare Flexible Spending Accountcheck_circleDependent Care Flexible Spending Accountcheck_circleShort Term Disability and Long Term Disability coveragecheck_circle401K Plancheck_circlePet insurancecheck_circleEmployee Stock Purchase Plancheck_circlePaid time offcheck_circleWellness resources
TransMedics, Inc. cover image
TransMedics, Inc. logo
Company

TransMedics, Inc.

Industry

Medical Equipment Manufacturing

Headquarters

Andover, MA

Open Roles

2

Redefining what's possible in organ transplantation

TransMedics, Inc. is a medical equipment manufacturing company headquartered in Andover, MA, dedicated to transforming organ transplant therapy for patients globally. The organization focuses on increasing access to viable donor organs for individuals awaiting transplantation by partnering with healthcare stakeholders to expand availability of healthy organs. This mission drives the development of advanced technologies and clinical care services designed to optimize donor organ viability. The company utilizes the Organ Care System (OCS), the only FDA-approved technology for lung, heart, and liver transplant indications in the United States. This innovation allows for the assessment and optimization of donor organs outside the human body, replacing the traditional static cold storage method. Supported by a nationwide team of clinical experts, 24/7 logistics support, and a dedicated air and ground transport network, TransMedics enables transplant centers to broaden their search criteria for viable donors. With over 25 years of commitment to innovation, the firm operates at the forefront of advancing organ transplantation. The National OCS Program integrates technology with logistics to help grow overall transplant volumes within the U.S. healthcare system. Through these efforts, the company aims to reduce organ wastage and improve outcomes for those in need of life-saving procedures.
View company profilearrow_forwardlanguageWebsitelinkLinkedIn
Quick Overview

Experience

8+ yrs (Lead)

Job Type

Full-Time

Skills Required

Machine LearningHipaaGDPRPythonScikit-LearnNumpy
$95k-154karrow_forward
TransMedics, Inc. has listed this Principal Data Science Engineer - AI/ML & Algorithms role as on-site.
How much experience is required for this Principal Data Science Engineer - AI/ML & Algorithms role?expand_more
Principal Data Science Engineer - AI/ML & Algorithms at TransMedics, Inc. typically requires 8+ years of relevant experience at the lead level.
What skills do you need for the Principal Data Science Engineer - AI/ML & Algorithms role at TransMedics, Inc.?expand_more
Key skills for Principal Data Science Engineer - AI/ML & Algorithms at TransMedics, Inc. include Machine Learning; Hipaa; GDPR; Python; Scikit-Learn; Numpy; Pandas; and Pytorch.
What category does the Principal Data Science Engineer - AI/ML & Algorithms role belong to?expand_more
Principal Data Science Engineer - AI/ML & Algorithms at TransMedics, Inc. is part of the it job category on Recrutus.

About TransMedics, Inc.

TransMedics, Inc. is a medical equipment manufacturing company headquartered in Andover, MA, dedicated to transforming organ transplant therapy for patients globally. The organization focuses on increasing access to viable donor organs for individuals awaiting transplantation by partnering with healthcare stakeholders to expand availability of healthy organs. This mission drives the development of advanced technologies and clinical care services designed to optimize donor organ viability.

The company utilizes the Organ Care System (OCS), the only FDA-approved technology for lung, heart, and liver transplant indications in the United States. This innovation allows for the assessment and optimization of donor organs outside the human body, replacing the traditional static cold storage method. Supported by a nationwide team of clinical experts, 24/7 logistics support, and a dedicated air and ground transport network, TransMedics enables transplant centers to broaden their search criteria for viable donors.

With over 25 years of commitment to innovation, the firm operates at the forefront of advancing organ transplantation. The National OCS Program integrates technology with logistics to help grow overall transplant volumes within the U.S. healthcare system. Through these efforts, the company aims to reduce organ wastage and improve outcomes for those in need of life-saving procedures.

Browse more roles: All TransMedics, Inc. jobs, it jobs on Recrutus.

Recrutus

Curating the world's most innovative career opportunities. We bridge the gap between visionary talent and industry-leading companies.

Search roles by city, category, skill, or job type — explore verified employers, salary benchmarks, and remote-friendly teams across India and beyond.

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Top states
Jobs in TexasJobs in New YorkJobs in CaliforniaJobs in FloridaJobs in North CarolinaJobs in TennesseeAll states →
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Company
About usFAQContactPrivacy policyUS privacy notice

Recrutus helps candidates discover roles that match their skills and helps teams reach qualified applicants faster. Browse by metro, discipline, or work style — from internships to senior leadership.

© 2026 Recrutus. All rights reserved.
Terms of serviceCookie policyAcceptable useDMCA policyEmployer termsCandidate terms
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SQL
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