Executive Director of Early Clinical Development

About Revolution Medicines

Revolution Medicines is a late-stage clinical oncology company dedicated to developing novel targeted therapies for patients with RAS-addicted cancers. Our R&D pipeline features a unique portfolio of RAS(ON) inhibitors designed to suppress diverse oncogenic variants of RAS proteins. Currently in clinical development are daraxonrasib (RMC-6236), a multi-selective inhibitor; elironrasib (RMC-6291), a G12C-selective inhibitor; zoldonrasib (RMC-9805), a G12D-selective inhibitor; and RMC-5127, a G12V-selective inhibitor.

As a new member of our team, you will join outstanding professionals united by a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.

About the Role

We are seeking an experienced drug developer and effective leader to serve as Executive Director of Early Clinical Development. In this critical role, you will support our clinical-stage and pre-clinical molecules by developing strategic plans and ensuring the efficient operational execution of clinical development programs. From early-stage studies to regulatory submissions and potential commercialization, you will play a pivotal role in shaping the future of our pipeline and driving the development of transformative therapies for patients.

Our Culture and Commitment

Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity/expression, national origin/ancestry, age, disability, marital status, medical condition, and veteran status. We foster a culture of collaboration, innovation, and excellence, where team members are inspired to make a meaningful difference in patients' lives.

Application and Security Notice

Please note that Revolution Medicines does not extend unsolicited employment offers and will never ask candidates to provide financial information, purchase equipment, or pay fees as part of the hiring process. All legitimate communication from Revolution Medicines will come from an official @revmed.com email address. If you believe you have been contacted by someone impersonating a Revolution Medicines recruiter, please report it to careers@revmed.com.

Privacy

Revolution Medicines takes the protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process, and use any personal data that you provide to us in accordance with our CCPA Notice.

Work location

Work model: Hybrid

1215, Dewey Street, Redwood City, San Mateo County, California, 94062, United States

Redwood City, California

Key Responsibilities

check_circleDevelop strategic plans and ensure operational execution of clinical development programs
check_circleLead, mentor, and manage a high-performing cross-functional clinical development team
check_circleEstablish and maintain relationships with clinical investigators and regulatory agencies
check_circleAnalyze and interpret clinical data to inform strategic decisions and program development
check_circlePartner with research, regulatory, commercial, and finance teams to ensure seamless execution
check_circleSteer molecules through Health Authority interactions and regulatory submissions
check_circleOversee clinical trial design, site selection, patient recruitment, and data management
check_circleManage clinical development timelines, resource allocation, and milestone achievement

Requirements

verifiedMD, PhD or similar advanced biomedical graduate degree
verified13+ years experience in pharmaceutical/biotech industry or academic background at Associate Professor level or higher
verifiedExperience authoring clinical development strategies
verifiedExtensive understanding of GCP, ICH, FDA, EMA guidelines
verifiedExperience leading Health Authority interactions
verifiedExperience publishing clinical trial results in peer-reviewed journals

Nice to Have

Experience in ongoing enhancements/development of core and sub-team processes, structures, systems, tools and other resources in the pharmaceutical/biotech industry. Experience creating clinical development strategy(ies) that led to label-enabling outcomes and commercialization. Experience submitting an NDA/BLA/MAA to global health authorities. Experience leading regulatory and internal partners/stakeholders in the completion and submission of regulatory documentation. Experience leading or overseeing data generation to address unmet medical needs and identify new or extended Clinical Development studies. Direct experience with Phase IV drug development. Ability to present a compelling business case and facilitate effective decision-making. Ability to serve as a company spokesperson both internally and externally. Demonstrated collaborative behaviors on enterprise-level strategic initiatives with a variety of internal and external partners and stakeholders. Demonstrated courage and conviction in past positions and responsibilities. Skilled in conflict resolution.

Benefits & Perks

check_circleRobust equity awardscheck_circleSignificant learning and development opportunities

Skills, education and keywords

Skills: Data Analysis, Clinical Trial Design, Clinical Trial Execution, Site Selection, Patient Recruitment, Data Management, Regulatory Compliance, GCP, Ich, Phase 1 Drug Development.

Education: PhD or similar advanced biomedical graduate degree required; MD or similar advanced biomedical graduate degree required.

Frequently asked questions about Executive Director, Early Clinical Development at Revolution Medicines

What does a Executive Director, Early Clinical Development at Revolution Medicines do?expand_more

In this Executive Director, Early Clinical Development at Revolution Medicines role, you will develop strategic plans and ensure operational execution of clinical development programs; lead, mentor, and manage a high-performing cross-functional clinical development team; establish and maintain relationships with clinical investigators and regulatory agencies; and analyze and interpret clinical data to inform strategic decisions and program development.

What are the requirements for this Executive Director, Early Clinical Development role?expand_more

Revolution Medicines is looking for candidates who meet the following requirements: MD, PhD or similar advanced biomedical graduate degree; 13+ years experience in pharmaceutical/biotech industry or academic background at Associate Professor level or higher; Experience authoring clinical development strategies; Extensive understanding of GCP, ICH, FDA, EMA guidelines; Experience leading Health Authority interactions; and Experience publishing clinical trial results in peer-reviewed journals.

Where is the Executive Director, Early Clinical Development role at Revolution Medicines located?expand_more

Executive Director, Early Clinical Development at Revolution Medicines is based in 1215, Dewey Street, Redwood City, San Mateo County, California, 94062, United States. This is a hybrid role.

Is this Executive Director, Early Clinical Development job remote, hybrid, or on-site?expand_more

Revolution Medicines has listed this Executive Director, Early Clinical Development role as hybrid.

How much experience is required for this Executive Director, Early Clinical Development role?expand_more

Executive Director, Early Clinical Development at Revolution Medicines typically requires 13+ years of relevant experience at the executive level.

What skills do you need for the Executive Director, Early Clinical Development role at Revolution Medicines?expand_more

Key skills for Executive Director, Early Clinical Development at Revolution Medicines include Data Analysis; Clinical Trial Design; Clinical Trial Execution; Site Selection; Patient Recruitment; Data Management; Regulatory Compliance; and GCP.

What education is required for Executive Director, Early Clinical Development at Revolution Medicines?expand_more

Educational requirements for this role: PhD or similar advanced biomedical graduate degree required; and MD or similar advanced biomedical graduate degree required.

What category does the Executive Director, Early Clinical Development role belong to?expand_more

Executive Director, Early Clinical Development at Revolution Medicines is part of the scientific & qa job category on Recrutus.

Executive Director, Early Clinical Development