Associate Director, Nonclinical Pharmacology
Not Disclosed•Full-TimeHybrid
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About Us
Oruka Therapeutics (Nasdaq: ORKA) is developing novel biologics designed to set a new standard for the treatment of chronic skin diseases. Our mission is to offer patients suffering from conditions like plaque psoriasis the greatest possible freedom from their condition by achieving high rates of complete disease clearance with dosing as infrequently as once or twice per year.
We are advancing a proprietary portfolio of potentially best-in-class antibodies engineered to target the core mechanisms underlying plaque psoriasis and other dermatologic and inflammatory diseases. As we build our core team, we are seeking top talent who are not just looking for a job, but an opportunity to be part of something bigger. We value individuals who are passionate about making a difference and eager to contribute to establishing an engaged, inclusive, and positive company culture.
About the Role
As an Associate Director, Nonclinical Pharmacology, you will be a key member of our Nonclinical team, driving the design and oversight of nonclinical pharmacology experiments and related assays. This role serves as a vital bridge between preclinical discovery and clinical development, engaging in translational research efforts to support clinical studies and influence the development of drugs through model-informed drug development (MIDD).
You will act as a company-wide immunology subject matter expert, partnering with key stakeholders including development teams, clinical scientists, and business development leaders. Your day-to-day will involve managing translational research efforts with academic collaborators, influencing the external scientific environment through publications and presentations, and supporting corporate initiatives requiring deep immunology expertise. This is an opportunity to shape the future of our company and make a real impact every day by helping bring new medicines to patients in a vibrant startup culture.
What We Offer
Join us in shaping the future of our company. We offer a chance to be part of a team where your work directly impacts bringing new medicines to patients. We provide a competitive salary and benefits package, along with opportunities for professional growth and development. Our supportive and inclusive team environment encourages everyone to bring their authentic selves to work.
Location & Work Model
This position is based in the United States and offers a hybrid or remote work model. If you live near one of our offices in Menlo Park, CA, or Waltham, MA, you will be required to be in-office three days per week. Remote candidates are also considered.
Equal Opportunity Employer
Oruka Therapeutics is committed to building a diverse and inclusive workforce. We are an equal opportunity employer and consider qualified applicants regardless of background, race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.
Skills, education and keywords
Skills: Graphpad Prism, Spotfire, Pharmacokinetics, Pharmacodynamics, Immunology, Pharmacology, Drug Development, Model-Informed Drug Development, Medical Writing, Clinical Operations.
Education: Bachelor's degree in life sciences with 10 years of experience; PhD degree in life sciences with 5 years of experience.
Frequently asked questions about Associate Director, Nonclinical Pharmacology at Oruka Therapeutics
What does a Associate Director, Nonclinical Pharmacology at Oruka Therapeutics do?expand_more
Day-to-day, the Associate Director, Nonclinical Pharmacology at Oruka Therapeutics will design and implement nonclinical pharmacology experiments with a focus on immunological endpoints; design and implement assays required for nonclinical, clinical, and cmc development projects; author nonclinical pharmacology aspects of clinical study protocols, analysis plans, and regulatory reports; and represent the company at scientific societies through publications, presentations, and external collaborations.
What are the requirements for this Associate Director, Nonclinical Pharmacology role?expand_more
Oruka Therapeutics is looking for candidates who meet the following requirements: Bachelor's degree and 10 years of experience in life sciences, immunology, or pharmacology; PhD degree and 5 years of experience in life sciences, immunology, or pharmacology; At least 4 years of experience in drug development; Strong immunology background and experience; Working knowledge of immunological experimental approaches; and Hands-on experience with GraphPad Prism, Spotfire, or other research software tools.