Principal or Senior Principal Scientist, Protein Drug Discovery
Not Disclosed•Full-TimeOn-site
location_on127, Lakeview Avenue, Huron Village, West Cambridge, Cambridge, Middlesex County, Massachusetts, 02140, United States
About the Team
Zealand Pharma is significantly expanding its global R&D capabilities, establishing new research units in Cambridge, Massachusetts. As part of this growth, the Molecular Platform Development group is being created to strengthen and advance diverse drug modality capabilities in metabolic disease.
This position sits within Discovery Research at the new Cambridge site. The team operates with a unique culture characterized by excellent teamwork and strong engagement. Making bonds is at the core of everything we do; we bond through curiosity and playfulness, allowing ourselves to challenge common thinking and drive future innovation. We are committed to an inclusive environment that fosters integrity and elevates technical standards across all teams and programs.
Work location
Work model: On-site
127, Lakeview Avenue, Huron Village, West Cambridge, Cambridge, Middlesex County, Massachusetts, 02140, United States
Cambridge, Massachusetts
Key Responsibilities
- check_circleDefine and lead protein drug discovery strategy aligned with metabolic disease portfolio
- check_circleDrive protein discovery programs from idea through lead-candidate selection
- check_circleProvide scientific leadership across therapeutic protein modalities including antibodies and bispecifics
- check_circleEstablish and grow discovery biologics platform capabilities including automation and display technologies
- check_circleBuild internal and external innovation by mentoring talent and forming strategic collaborations
- check_circleGuide protein engineering, developability assessment, and structure-function optimization
Requirements
- verifiedPhD in Protein Science, Biochemistry, Structural Biology, Biophysics, Bioengineering, or related field
- verified6+ years post-degree experience (Principal) or 8+ years (Senior Principal) in protein drug discovery
- verifiedDemonstrated track record advancing projects from concept to clinical development
- verifiedDeep expertise in protein engineering and structure-informed design
- verifiedExperience with high-throughput expression, purification, analytical characterization, and developability assessment
- verifiedHands-on knowledge of hit-finding and affinity maturation approaches
- verifiedAbility to interpret and apply computational modeling/design insights
Nice to Have
Postdoctoral training
Similar Job Opportunities
Skills, education and keywords
Skills: Protein Drug Discovery, Protein Engineering, Phage Display, Yeast Display, Computational Modeling, Affinity Maturation, High-Throughput Expression, Purification, Analytical Characterization, Biophysical Assessment.
Education: PhD in Protein Science, Biochemistry, Structural Biology, Biophysics, Bioengineering, or related field required.
Frequently asked questions about Principal or Senior Principal Scientist, Protein Drug Discovery at Zealand Pharma
What does a Principal or Senior Principal Scientist, Protein Drug Discovery at Zealand Pharma do?expand_more
A Principal or Senior Principal Scientist, Protein Drug Discovery at Zealand Pharma is responsible for the following: Define and lead protein drug discovery strategy aligned with metabolic disease portfolio; Drive protein discovery programs from idea through lead-candidate selection; Provide scientific leadership across therapeutic protein modalities including antibodies and bispecifics; and Establish and grow discovery biologics platform capabilities including automation and display technologies.
What are the requirements for this Principal or Senior Principal Scientist, Protein Drug Discovery role?expand_more
Zealand Pharma is looking for candidates who meet the following requirements: PhD in Protein Science, Biochemistry, Structural Biology, Biophysics, Bioengineering, or related field; 6+ years post-degree experience (Principal) or 8+ years (Senior Principal) in protein drug discovery; Demonstrated track record advancing projects from concept to clinical development; Deep expertise in protein engineering and structure-informed design; Experience with high-throughput expression, purification, analytical characterization, and developability assessment; and Hands-on knowledge of hit-finding and affinity maturation approaches.
Where is the Principal or Senior Principal Scientist, Protein Drug Discovery role at Zealand Pharma located?expand_more
Principal or Senior Principal Scientist, Protein Drug Discovery at Zealand Pharma is based in 127, Lakeview Avenue, Huron Village, West Cambridge, Cambridge, Middlesex County, Massachusetts, 02140, United States. This is a on-site role.
Is this Principal or Senior Principal Scientist, Protein Drug Discovery job remote, hybrid, or on-site?expand_more
Zealand Pharma has listed this Principal or Senior Principal Scientist, Protein Drug Discovery role as on-site.
How much experience is required for this Principal or Senior Principal Scientist, Protein Drug Discovery role?expand_more
Principal or Senior Principal Scientist, Protein Drug Discovery at Zealand Pharma typically requires 6–8 years of relevant experience at the lead level.
What skills do you need for the Principal or Senior Principal Scientist, Protein Drug Discovery role at Zealand Pharma?expand_more
Key skills for Principal or Senior Principal Scientist, Protein Drug Discovery at Zealand Pharma include Protein Drug Discovery; Protein Engineering; Phage Display; Yeast Display; Computational Modeling; Affinity Maturation; High-Throughput Expression; and Purification.
What education is required for Principal or Senior Principal Scientist, Protein Drug Discovery at Zealand Pharma?expand_more
Educational requirements for this role: PhD in Protein Science, Biochemistry, Structural Biology, Biophysics, Bioengineering, or related field required.
What category does the Principal or Senior Principal Scientist, Protein Drug Discovery role belong to?expand_more
Principal or Senior Principal Scientist, Protein Drug Discovery at Zealand Pharma is part of the scientific & qa job category on Recrutus.
About Zealand Pharma
Zealand Pharma is a biotechnology research firm headquartered in Søborg, Copenhagen, Denmark, dedicated to developing next-generation peptide medicines. The organization focuses on creating therapeutic solutions that address significant unmet medical needs, specifically targeting obesity, chronic inflammation, and select rare diseases. Through a pipeline of ten drug candidates that have advanced into clinical development, the company has successfully brought two products to market.
Strategic collaboration is central to Zealand Pharma's operational model, with major obesity programs supported by established partners such as Roche and Boehringer Ingelheim. The company maintains a presence in the United States alongside its Danish headquarters, facilitating global engagement in drug discovery and development. Their approach emphasizes the importance of connection, whether in forming research partnerships, engaging with patients, or fostering internal team cohesion.
For detailed information regarding their business activities and product portfolio, stakeholders can refer to the official website or connect via professional networks. The firm continues to expand its footprint in the biotechnology sector by advancing innovative treatments from discovery through clinical stages.
Browse more roles: All Zealand Pharma jobs, scientific & qa jobs on Recrutus.