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  1. Home
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  5. Data Scientist
AstraZeneca logo

Data Scientist

Not Disclosed•Full-TimeOn-site

location_onOcean Court, Downtown Santa Monica, Santa Monica, Los Angeles County, California, 90401, United States

Apply Now

About the Role

This position serves as a strategic bridge between advanced computational analysis and clinical decision-making. You will lead bioinformatic and data science efforts centered on single-cell RNA-seq (scRNA-seq) and T-cell receptor sequencing (scTCR-seq). The role exists to transform complex transcriptomic and immune repertoire data into actionable biological insights that drive cell therapy research and clinical outcomes.

In this capacity, you will design and implement custom analytical models tailored to immunology questions, integrating scRNA-seq with complementary data types such as bulk RNA-seq and clinical metadata. Your work will directly support translational programs by characterizing T-cell clonality, diversity, and dynamics, while linking receptor features to specific transcriptional states and phenotypes. You will be responsible for establishing reproducible, scalable data architectures on cloud or high-performance computing resources, ensuring that analytical pipelines meet the rigor required for regulated environments.

Working Environment

You will operate within a fast-paced, collaborative environment where a team-oriented mindset is essential. Success in this role requires the ability to work independently while maintaining close collaboration with biologists, clinicians, and cross-functional teams. A key aspect of the day-to-day involves translating complex analytical concepts into clear reports, visualizations, and presentations for non-expert stakeholders. Flexibility is crucial as you adjust priorities to meet evolving project needs and proactively incorporate emerging single-cell technologies to improve analytical approaches.

Work location

Work model: On-site

location_on

Ocean Court, Downtown Santa Monica, Santa Monica, Los Angeles County, California, 90401, United States

Santa Monica, California

Key Responsibilities

  • check_circleApply advanced statistical, machine learning, and AI methods to identify cell states and biomarkers
  • check_circleDesign and implement custom analytical tools and models for cell therapy research
  • check_circleEstablish and maintain reproducible, scalable data architectures using cloud platforms
  • check_circleBuild and manage code repositories, documentation, and best practices for data analysis
  • check_circleCommunicate complex analytical methods and findings through reports and presentations
  • check_circleLead bioinformatic and data science efforts focused on single-cell RNA-seq data analysis
  • check_circleIntegrate single-cell data with genomics and clinical metadata to support translational decision-making
  • check_circleAnalyze single-cell TCR sequencing data to characterize T-cell clonality and diversity

Requirements

  • verified5+ years experience with BS/BA
  • verified3+ years experience with MS/MA
  • verified1+ year experience with PhD
  • verifiedBS/BA in data science, computational biology, bioengineering, or related field
  • verifiedMS/MA in data science, computational biology, bioengineering, or related field
  • verifiedPhD in data science, computational biology, bioengineering, or related field
  • verifiedProficiency in Python
  • verifiedProficiency in R
  • verifiedExperience with cloud computing platforms
  • verifiedExperience with high-performance computing clusters
  • verifiedDeep hands-on experience with single-cell RNA-seq data analysis
  • verifiedStrong background in NGS workflows
  • verifiedProficiency with single-cell immune repertoire sequencing concepts
  • verifiedExpertise in bioinformatics and computational biology tools
  • verifiedSolid understanding of statistical methods

Nice to Have

Experience in immunology, immune‑oncology, or cell therapy research.

AstraZeneca cover image
AstraZeneca logo
Company

AstraZeneca

Industry

Pharmaceutical Manufacturing

Headquarters

Cambridge, Cambridgeshire

Open Roles

1

AstraZeneca is advancing healthcare through scientific innovation in pharmaceutical manufacturing, with a focus on developing solutions for patients, communities, and environmental sustainability. Based in Cambridge, Cambridgeshire, the company prioritizes research-driven approaches to address global health challenges while balancing societal and planetary needs. Committed to ethical practices and measurable impact, AstraZeneca collaborates across industries to deliver therapies that improve lives. For more information about its mission and initiatives, visit www.astrazeneca.com.
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Quick Overview

Experience

1+ yrs (Senior)

Education

PhD in data science, computational biology, bioengineering, or related field (1+ year exp)

Job Type

Full-Time

Skills Required

Single‑cell Rna‑seqMachine LearningAiSingle‑cell TCR SequencingNGSPython
Recrutus

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