
location_on5359, West Frontage Road Northwest, Rochester, Olmsted County, Minnesota, 55901, United States
We are seeking a motivated postdoctoral Research Fellow to join the Translational Omics Program (TOP) and the Department of Medicine (DOM)–led Omics-based Research for Identifying Genomic Insights and New Therapies (ORIGIN) initiative at Mayo Clinic.
ORIGIN is a bench-to-bedside translational research program designed to bridge multi-omics discovery with real-time clinical application across DOM divisions. The program leverages deep molecular profiling, functional genomics, and collaborative translational pipelines to improve diagnosis, enable targeted therapies, and accelerate discovery for patients with serious, complex, and rare diseases.
Research fellows will be embedded in a highly multidisciplinary environment that integrates clinical medicine, genomics, functional biology, informatics, and population-scale data resources. While computational and AI-enabled approaches may be incorporated, the primary emphasis of this role is on translational biology and genomics rather than method development alone.
This position provides advanced training in translational omics research and is intended to prepare fellows for independent academic, translational, or industry research careers. Potential projects under ORIGIN are diverse and evolve based on clinical need, emerging discoveries, and collaborative opportunities across Mayo Clinic.
As a Research Fellow at Mayo Clinic, you will work within the research program of a principal investigator. The role is designed to help you develop a strong publication record and become competitive for external funding. You will engage in a dynamic environment where research priorities shift to address urgent clinical needs and new scientific frontiers.
To complete your application, please submit a current curriculum vitae with bibliography, proof of doctoral degree (or documentation of degree completion), and letters of recommendation as requested by the hiring principal investigator. Proof of English proficiency is required for J‑1–sponsored trainees.
Work model: On-site
5359, West Frontage Road Northwest, Rochester, Olmsted County, Minnesota, 55901, United States
Rochester, Minnesota
Skills: Translational Omics, Genomics, Functional Genomics, Multi-Omics, Transcriptomics, Proteomics, Metabolomics, Genetic Variant Interpretation, Computational Biology, Population-Scale Data.
Education: PhD in genetics, genomics, molecular biology, computational biology, or related biomedical field required; MD/PhD in genetics, genomics, molecular biology, computational biology, or related biomedical field required; MD in genetics, genomics, molecular biology, computational biology, or related biomedical field required.