Overview Join the HJF Team HJF is seeking a Postdoctoral Fellow responsible for initiating and carrying out research projects in collaboration with a research team. This position will be in support of the Symes Laboratory in the Department of Pharmacology. The incumbent will participate in Department of Defense funded projects, to elucidate the molecular mechanisms of blast injury on IPSC derived 3D-brain like cultures and on mouse brains. Using imaging, biochemical, genetic and epigenetic techniques, the project seeks to understand and identify novel pathways and potential biomarkers for blast injury to the brain. Investigation will include the study of metabolic and mitochondrial responses to blast, inflammatory and autophagy changes, and alterations in neuronal microtubule structure and function. The successful candidate will have the opportunity to design and develop experiments, publish and present their research at scientific meetings. Interest in neuroscience is a distinct advantage. The Henry M. Jackson Foundation for the Advancement of Military Medicine (HJF) is a nonprofit organization dedicated to advancing military medicine. We serve military, medical, academic and government clients by administering, managing and supporting preeminent scientific programs that benefit members of the armed forces and civilians alike. Responsibilities Conduct experiments in human 2D and 3D tissue culture using cutting edge techniques for molecular pathway analyses of cellular responses to injury. Perform highly skilled and specialized laboratory research utilizing and designing experimental protocols which will involve specialized procedures such as confocal microscopy, mitochondrial isolation, analysis of RNA and protein expression, and isolation of cells from mouse brain. Formulate experimental hypotheses, design, and execute experimental protocols. Make scientific observations, maintain detailed workbooks/documentation, and ensure documentation fulfills generally accepted professional/industry standards. Analyze and interpret experimental data, including statistical analyses. Train and supervise laboratory technicians, as needed. Prepare written reports and manuscripts for submission to scientific journals. May perform other duties and responsibilities as assigned or directed by the supervisor. Qualifications Education and Experience Doctoral degree Minimum of 0-5 years experience required. Required Knowledge, Skills and Abilities Experience with tissue culture (an advantage if has worked with iPSCs). Significant experience with a variety of biochemical and molecular biology techniques. Experience with microscopy (knowledge of confocal microscopy very advantageous). Highly motivated to perform cutting edge, independent research. Excellent communication skills. Ability to troubleshoot technical procedures. Ability to work independently and supervise others. The ability to obtain and maintain a T1 Public Trust Clearance. Work Environment This position will take place primarily in a laboratory setting. Compensation The annual salary range for this position is $50,100-$59,000. Actual salary will be determined based on experience, education, etc. Benefits HJF offers a comprehensive suite of benefits focused on your health and well-being, from medical, dental, and vision coverage to health savings and retirement plans, and more. Some HJF employees are required to be fully vaccinated against COVID-19. Proof of vaccination or an approved religious or medical accommodation may be required. Employment with HJF is contingent upon successful completion of a background check, which may include, but is not limited to, contacting your professional references, verification of previous employment, education and credentials, a criminal background check, and a department of motor vehicle (DMV) check if applicable. Equal Opportunity Employer/Protected Veterans/Individuals with Disabilities J-18808-Ljbffr